PDB 4oqb

PDB Information

PDB4OQB
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and Structure-Activity Relationship of Novel 2,3-Dihydrobenzofuran-7-carboxamide and 2,3-Dihydrobenzofuran-3(2H)-one-7-carboxamide Derivatives as Poly(ADP-ribose)polymerase-1 Inhibitors.
Patel, M.R., Bhatt, A., Steffen, J.D., Chergui, A., Murai, J., Pommier, Y., Pascal, J.M., Trombetta, L.D., Fronczek, F.R., Talele, T.T.
J.Med.Chem.
HeaderTransferase/Dna/Transferase Inhibitor
Released2014-02-07
Resolution3.360
CATH Insert Date20 Jul, 2014

PDB Images (17)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 21 Jul, 2014 Chopped
C 21 Jul, 2014 Chopped
D 21 Jul, 2014 Chopped
F 21 Jul, 2014 Chopped
M 21 Jul, 2014 Rejected
N 21 Jul, 2014 Rejected

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
4oqbA01 04 Jan, 2017 3.30.1740.10 Assigned
4oqbA02 04 Jan, 2017 Holding pen
4oqbC01 03 Aug, 2014 Holding pen
4oqbC02 03 Aug, 2014 3.90.228.10 Assigned
4oqbC03 03 Aug, 2014 1.20.142.10 Assigned
4oqbD01 04 Jan, 2017 3.30.1740.10 Assigned
4oqbD02 04 Jan, 2017 Holding pen
4oqbF01 03 Aug, 2014 Holding pen
4oqbF02 03 Aug, 2014 3.90.228.10 Assigned
4oqbF03 03 Aug, 2014 1.20.142.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1