PDB 4oqa

PDB Information

PDB4OQA
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and Structure-Activity Relationship of Novel 2,3-Dihydrobenzofuran-7-carboxamide and 2,3-Dihydrobenzofuran-3(2H)-one-7-carboxamide Derivatives as Poly(ADP-ribose)polymerase-1 Inhibitors.
Patel, M.R., Bhatt, A., Steffen, J.D., Chergui, A., Murai, J., Pommier, Y., Pascal, J.M., Trombetta, L.D., Fronczek, F.R., Talele, T.T.
J.Med.Chem.
HeaderTransferase/Dna/Transferase Inhibitor
Released2014-02-07
Resolution3.650
CATH Insert Date20 Jul, 2014

PDB Images (17)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 21 Jul, 2014 Chopped
C 21 Jul, 2014 Chopped
D 21 Jul, 2014 Chopped
F 21 Jul, 2014 Chopped
M 21 Jul, 2014 Rejected
N 21 Jul, 2014 Rejected

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
4oqaA01 04 Jan, 2017 3.30.1740.10 Assigned
4oqaA02 04 Jan, 2017 Holding pen
4oqaC01 03 Aug, 2014 Holding pen
4oqaC02 03 Aug, 2014 3.90.228.10 Assigned
4oqaC03 03 Aug, 2014 1.20.142.10 Assigned
4oqaD01 04 Jan, 2017 3.30.1740.10 Assigned
4oqaD02 04 Jan, 2017 Holding pen
4oqaF01 03 Aug, 2014 Holding pen
4oqaF02 03 Aug, 2014 3.90.228.10 Assigned
4oqaF03 03 Aug, 2014 1.20.142.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1