PDB 4oq5

PDB Information

PDB4OQ5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein.
Petros, A.M., Swann, S.L., Song, D., Swinger, K., Park, C., Zhang, H., Wendt, M.D., Kunzer, A.R., Souers, A.J., Sun, C.
Bioorg.Med.Chem.Lett.
HeaderApoptosis/Inhibitor
Released2014-02-07
Resolution2.860
CATH Insert Date16 Mar, 2014

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 17 Mar, 2014 Chopped
B 17 Mar, 2014 Chopped
C 17 Mar, 2014 Chopped
D 17 Mar, 2014 Chopped
E 17 Mar, 2014 Chopped
F 17 Mar, 2014 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4oq5A01 25 Apr, 2014 1.10.437.10 Assigned
4oq5B01 25 Apr, 2014 1.10.437.10 Assigned
4oq5C01 25 Apr, 2014 1.10.437.10 Assigned
4oq5D01 25 Apr, 2014 1.10.437.10 Assigned
4oq5E01 25 Apr, 2014 1.10.437.10 Assigned
4oq5F01 25 Apr, 2014 1.10.437.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820 MCL1_HUMAN Homo sapiens Induced myeloid leukemia cell differentiation protein Mcl-1
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