PDB Information

PDB4OHM
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 3. Structure-activity relationships within the aryl carbinol region of the N-arylsulfonamido-N'-arylpiperazine series.
Nishimura, N., Norman, M.H., Liu, L., Yang, K.C., Ashton, K.S., Bartberger, M.D., Chmait, S., Chen, J., Cupples, R., Fotsch, C., Helmering, J., Jordan, S.R., Kunz, R.K., Pennington, L.D., Poon, S.F., Siegmund, A., Sivits, G., Lloyd, D.J., Hale, C., St Jean, D.J.
J.Med.Chem.
HeaderCarbohydrate Binding Protein/Inhibitor
Released2014-01-17
Resolution2.400
CATH Insert Date10 Aug, 2014

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Aug, 2014 Chopped
B 11 Aug, 2014 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4ohmA01 19 Aug, 2014 3.40.50.10490 Assigned
4ohmA02 19 Aug, 2014 Holding pen
4ohmA03 19 Aug, 2014 Holding pen
4ohmB01 20 Aug, 2014 3.40.50.10490 Assigned
4ohmB02 20 Aug, 2014 Holding pen
4ohmB03 20 Aug, 2014 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q14397 GCKR_HUMAN Homo sapiens Glucokinase regulatory protein
Q14397 GCKR_HUMAN Homo sapiens Glucokinase regulatory protein