PDB Information

PDB4OHK
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 3. Structure-activity relationships within the aryl carbinol region of the N-arylsulfonamido-N'-arylpiperazine series.
Nishimura, N., Norman, M.H., Liu, L., Yang, K.C., Ashton, K.S., Bartberger, M.D., Chmait, S., Chen, J., Cupples, R., Fotsch, C., Helmering, J., Jordan, S.R., Kunz, R.K., Pennington, L.D., Poon, S.F., Siegmund, A., Sivits, G., Lloyd, D.J., Hale, C., St Jean, D.J.
J.Med.Chem.
HeaderCarbohydrate Binding Protein/Inhibitor
Released2014-01-17
Resolution2.800
CATH Insert Date19 Oct, 2014

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 20 Oct, 2014 Chopped
B 20 Oct, 2014 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4ohkA01 21 Oct, 2014 3.40.50.10490 Assigned
4ohkA02 21 Oct, 2014 Holding pen
4ohkA03 21 Oct, 2014 Holding pen
4ohkB01 21 Oct, 2014 3.40.50.10490 Assigned
4ohkB02 21 Oct, 2014 Holding pen
4ohkB03 21 Oct, 2014 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q14397 GCKR_HUMAN Homo sapiens Glucokinase regulatory protein
Q14397 GCKR_HUMAN Homo sapiens Glucokinase regulatory protein