PDB 4oba

PDB Information

PDB4OBA
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Selective and Potent Morpholinone Inhibitors of the MDM2-p53 Protein-Protein Interaction.
Gonzalez, A.Z., Eksterowicz, J., Bartberger, M.D., Beck, H.P., Canon, J., Chen, A., Chow, D., Duquette, J., Fox, B.M., Fu, J., Huang, X., Houze, J.B., Jin, L., Li, Y., Li, Z., Ling, Y., Lo, M.C., Long, A.M., McGee, L.R., McIntosh, J., McMinn, D.L., Oliner, J.D., Osgood, T., Rew, Y., Saiki, A.Y., Shaffer, P., Wortman, S., Yakowec, P., Yan, X., Ye, Q., Yu, D., Zhao, X., Zhou, J., Olson, S.H., Medina, J.C., Sun, D.
J.Med.Chem.
HeaderLigase/Ligase Inhibitor
Released2014-01-07
Resolution1.600
CATH Insert Date23 Mar, 2014

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 24 Mar, 2014 Chopped
B 24 Mar, 2014 Chopped
C 24 Mar, 2014 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4obaA00 17 Apr, 2014 1.10.245.10 Assigned
4obaB00 25 Apr, 2014 1.10.245.10 Assigned
4obaC00 25 Apr, 2014 1.10.245.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2