PDB 4o2a

PDB Information

PDB4O2A
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
The Novel Microtubule-Destabilizing Drug BAL27862 Binds to the Colchicine Site of Tubulin with Distinct Effects on Microtubule Organization.
Prota, A.E., Danel, F., Bachmann, F., Bargsten, K., Buey, R.M., Pohlmann, J., Reinelt, S., Lane, H., Steinmetz, M.O.
J.Mol.Biol.
HeaderCell Cycle/Inhibitor
Released2013-12-17
Resolution2.500
CATH Insert Date09 Mar, 2014

PDB Images (23)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 10 Mar, 2014 Chopped
B 10 Mar, 2014 Chopped
C 10 Mar, 2014 Chopped
D 10 Mar, 2014 Chopped
E 10 Mar, 2014 Chopped
F 10 Mar, 2014 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
4o2aA01 25 Apr, 2014 3.40.50.1440 Assigned
4o2aA02 25 Apr, 2014 3.30.1330.20 Assigned
4o2aA03 25 Apr, 2014 1.10.287.600 Assigned
4o2aB01 25 Apr, 2014 3.40.50.1440 Assigned
4o2aB02 25 Apr, 2014 3.30.1330.20 Assigned
4o2aB03 25 Apr, 2014 1.10.287.600 Assigned
4o2aC01 17 Apr, 2014 3.40.50.1440 Assigned
4o2aC02 17 Apr, 2014 3.30.1330.20 Assigned
4o2aC03 17 Apr, 2014 1.10.287.600 Assigned
4o2aD01 25 Apr, 2014 3.40.50.1440 Assigned
4o2aD02 25 Apr, 2014 3.30.1330.20 Assigned
4o2aD03 25 Apr, 2014 1.10.287.600 Assigned
4o2aE01 17 Apr, 2014 6.10.280.30 Assigned
4o2aF01 17 Apr, 2014 3.40.50.11480 Assigned
4o2aF02 17 Apr, 2014 3.30.470.20 Assigned
4o2aF03 17 Apr, 2014 3.30.1490.20 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
E1BQ43 E1BQ43_CHICK Gallus gallus Uncharacterized protein
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
P63043 STMN4_RAT Rattus norvegicus Stathmin-4