PDB 4o0t

PDB Links
Overview

PDB Information

PDB	4O0T
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors. Staben, S.T., Feng, J.A., Lyle, K., Belvin, M., Boggs, J., Burch, J.D., Chua, C.C., Cui, H., Dipasquale, A.G., Friedman, L.S., Heise, C., Koeppen, H., Kotey, A., Mintzer, R., Oh, A., Roberts, D.A., Rouge, L., Rudolph, J., Tam, C., Wang, W., Xiao, Y., Young, A., Zhang, Y., Hoeflich, K.P. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2013-12-14
Resolution	2.600
CATH Insert Date	16 Feb, 2014

PDB Images (7)

Image of CATH 4o0t

4o0t

PDB 4o0t

Image of CATH 4o0tA

4o0tA

PDB Chain 4o0tA

Image of CATH 4o0tB

4o0tB

PDB Chain 4o0tB

Image of CATH 4o0tA01

4o0tA01

CATH Domain 4o0tA01

Image of CATH 4o0tA02

4o0tA02

CATH Domain 4o0tA02

Image of CATH 4o0tB01

4o0tB01

CATH Domain 4o0tB01

Image of CATH 4o0tB02

4o0tB02

CATH Domain 4o0tB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	17 Feb, 2014	Chopped
B	17 Feb, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4o0tA01	07 Mar, 2014	3.30.200.20	Assigned
4o0tA02	07 Mar, 2014	1.10.510.10	Assigned
4o0tB01	07 Mar, 2014	3.30.200.20	Assigned
4o0tB02	07 Mar, 2014	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q13153	PAK1_HUMAN	Homo sapiens	Serine/threonine-protein kinase PAK 1
Q13153	PAK1_HUMAN	Homo sapiens	Serine/threonine-protein kinase PAK 1