PDB 4o0t

PDB Information

PDB4O0T
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors.
Staben, S.T., Feng, J.A., Lyle, K., Belvin, M., Boggs, J., Burch, J.D., Chua, C.C., Cui, H., Dipasquale, A.G., Friedman, L.S., Heise, C., Koeppen, H., Kotey, A., Mintzer, R., Oh, A., Roberts, D.A., Rouge, L., Rudolph, J., Tam, C., Wang, W., Xiao, Y., Young, A., Zhang, Y., Hoeflich, K.P.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2013-12-14
Resolution2.600
CATH Insert Date16 Feb, 2014

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 17 Feb, 2014 Chopped
B 17 Feb, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4o0tA01 07 Mar, 2014 3.30.200.20 Assigned
4o0tA02 07 Mar, 2014 1.10.510.10 Assigned
4o0tB01 07 Mar, 2014 3.30.200.20 Assigned
4o0tB02 07 Mar, 2014 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q13153 PAK1_HUMAN Homo sapiens Serine/threonine-protein kinase PAK 1
Q13153 PAK1_HUMAN Homo sapiens Serine/threonine-protein kinase PAK 1