PDB Information

PDB4O09
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Identification of Novel HSP90 alpha / beta Isoform Selective Inhibitors Using Structure-Based Drug Design. Demonstration of Potential Utility in Treating CNS Disorders such as Huntington's Disease.
Ernst, J.T., Neubert, T., Liu, M., Sperry, S., Zuccola, H., Turnbull, A., Fleck, B., Kargo, W., Woody, L., Chiang, P., Tran, D., Chen, W., Snyder, P., Alcacio, T., Nezami, A., Reynolds, J., Alvi, K., Goulet, L., Stamos, D.
J.Med.Chem.
HeaderChaperone/Chaperone Inhibitor
Released2013-12-13
Resolution1.960
CATH Insert Date13 Apr, 2014

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 14 Apr, 2014 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4o09A00 17 Apr, 2014 3.30.565.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P07900 HS90A_HUMAN Homo sapiens Heat shock protein HSP 90-alpha