PDB Information

PDB4NUS
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Novel potent and selective inhibitors of p90 ribosomal S6 kinase reveal the heterogeneity of RSK function in MAPK-driven cancers.
Aronchik, I., Appleton, B.A., Basham, S.E., Crawford, K., Del Rosario, M., Doyle, L.V., Estacio, W.F., Lan, J., Lindvall, M.K., Luu, C.A., Ornelas, E., Venetsanakos, E., Shafer, C.M., Jefferson, A.B.
Mol Cancer Res
HeaderTransferase/Transferase Inhibitor
Released2013-12-04
Resolution2.390
CATH Insert Date09 Mar, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 10 Mar, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4nusA01 17 Apr, 2014 3.30.200.20 Assigned
4nusA02 17 Apr, 2014 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P51812 KS6A3_HUMAN Homo sapiens Ribosomal protein S6 kinase alpha-3