PDB Information

PDB4NEU
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of Small Molecule RIP1 Kinase Inhibitors for the Treatment of Pathologies Associated with Necroptosis.
Harris, P.A., Bandyopadhyay, D., Berger, S.B., Campobasso, N., Capriotti, C.A., Cox, J.A., Dare, L., Finger, J.N., Hoffman, S.J., Kahler, K.M., Lehr, R., Lich, J.D., Nagilla, R., Nolte, R.T., Ouellette, M.T., Pao, C.S., Schaeffer, M.C., Smallwood, A., Sun, H.H., Swift, B.A., Totoritis, R.D., Ward, P., Marquis, R.W., Bertin, J., Gough, P.J.
ACS Med Chem Lett
HeaderTransferase
Released2013-10-30
Resolution2.570
CATH Insert Date24 Nov, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 25 Nov, 2013 Chopped
B 25 Nov, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4neuA00 03 Dec, 2013 1.10.510.10 Assigned
4neuB00 03 Dec, 2013 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q13546 RIPK1_HUMAN Homo sapiens Receptor-interacting serine/threonine-protein kinase 1
Q13546 RIPK1_HUMAN Homo sapiens Receptor-interacting serine/threonine-protein kinase 1