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PDB Information
| PDB | 4NEE |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Rattus norvegicus |
| Primary Citation |
How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4.
Ren, X., Park, S.Y., Bonifacino, J.S., Hurley, J.H.
Elife
|
| Header | Viral Protein/Protein Transport |
| Released | 2013-10-29 |
| Resolution | 2.880 |
| CATH Insert Date | 02 Feb, 2014 |
PDB Images (25)
4neeA00
CATH Domain 4neeA00
4neeB00
CATH Domain 4neeB00
4neeC00
CATH Domain 4neeC00
4neeD00
CATH Domain 4neeD00
4neeE00
CATH Domain 4neeE00
4neeF00
CATH Domain 4neeF00
4neeG00
CATH Domain 4neeG00
4neeH00
CATH Domain 4neeH00
4neeI00
CATH Domain 4neeI00
4neeJ00
CATH Domain 4neeJ00
4neeK00
CATH Domain 4neeK00
4neeL00
CATH Domain 4neeL00
PDB Chains (12)
| Chain ID | Date inserted into CATH | CATH Status |
| A | 03 Feb, 2014 | Chopped
|
| B | 03 Feb, 2014 | Chopped
|
| C | 03 Feb, 2014 | Chopped
|
| D | 03 Feb, 2014 | Chopped
|
| E | 03 Feb, 2014 | Chopped
|
| F | 03 Feb, 2014 | Chopped
|
| G | 03 Feb, 2014 | Chopped
|
| H | 03 Feb, 2014 | Chopped
|
| I | 03 Feb, 2014 | Chopped
|
| J | 03 Feb, 2014 | Chopped
|
| K | 03 Feb, 2014 | Chopped
|
| L | 03 Feb, 2014 | Chopped
|
CATH Domains (12)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
| 4neeA00 | 15 May, 2014 | 1.25.10.10 | Assigned
|
| 4neeB00 | 15 May, 2014 | 1.25.10.10 | Assigned
|
| 4neeC00 | 07 Mar, 2014 | 3.30.62.10 | Assigned
|
| 4neeD00 | 07 Mar, 2014 | 3.30.450.60 | Assigned
|
| 4neeE00 | 07 Mar, 2014 | 3.30.62.10 | Assigned
|
| 4neeF00 | 07 Mar, 2014 | 3.30.450.60 | Assigned
|
| 4neeG00 | 15 May, 2014 | 1.25.10.10 | Assigned
|
| 4neeH00 | 07 Mar, 2014 | 3.30.62.10 | Assigned
|
| 4neeI00 | 07 Mar, 2014 | 3.30.450.60 | Assigned
|
| 4neeJ00 | 15 May, 2014 | 1.25.10.10 | Assigned
|
| 4neeK00 | 07 Mar, 2014 | 3.30.62.10 | Assigned
|
| 4neeL00 | 07 Mar, 2014 | 3.30.450.60 | Assigned
|
UniProtKB Entries (12)
| Accession |
Gene ID |
Taxon |
Description |
| P18484 |
AP2A2_RAT |
Rattus norvegicus |
AP-2 complex subunit alpha-2 |
| P18484 |
AP2A2_RAT |
Rattus norvegicus |
AP-2 complex subunit alpha-2 |
| P04601 |
NEF_HV1H2 |
HIV-1 M:B_HXB2R |
Protein Nef |
| P62744 |
AP2S1_RAT |
Rattus norvegicus |
AP-2 complex subunit sigma |
| P62744 |
AP2S1_RAT |
Rattus norvegicus |
AP-2 complex subunit sigma |
| P18484 |
AP2A2_RAT |
Rattus norvegicus |
AP-2 complex subunit alpha-2 |
| P04601 |
NEF_HV1H2 |
HIV-1 M:B_HXB2R |
Protein Nef |
| P62744 |
AP2S1_RAT |
Rattus norvegicus |
AP-2 complex subunit sigma |
| P62744 |
AP2S1_RAT |
Rattus norvegicus |
AP-2 complex subunit sigma |
| P18484 |
AP2A2_RAT |
Rattus norvegicus |
AP-2 complex subunit alpha-2 |
| P04601 |
NEF_HV1H2 |
HIV-1 M:B_HXB2R |
Protein Nef |
| P04601 |
NEF_HV1H2 |
HIV-1 M:B_HXB2R |
Protein Nef |