PDB Information

PDB4NE9
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro.
Schroeder, C.I., Swedberg, J.E., Withka, J.M., Rosengren, K.J., Akcan, M., Clayton, D.J., Daly, N.L., Cheneval, O., Borzilleri, K.A., Griffor, M., Stock, I., Colless, B., Walsh, P., Sunderland, P., Reyes, A., Dullea, R., Ammirati, M., Liu, S., McClure, K.F., Tu, M., Bhattacharya, S.K., Liras, S., Price, D.A., Craik, D.J.
Chem.Biol.
HeaderHydrolase
Released2013-10-28
Resolution2.600
CATH Insert Date14 Sep, 2014

PDB Images (12)

PDB Prints

PDB Chains (5)

Chain ID Date inserted into CATH CATH Status
A 15 Sep, 2014 Chopped
B 15 Sep, 2014 Chopped
C 15 Sep, 2014 Chopped
D 15 Sep, 2014 Rejected
P 15 Sep, 2014 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4ne9A01 16 Sep, 2014 3.40.50.200 Assigned
4ne9A02 16 Sep, 2014 2.60.120.690 Assigned
4ne9B01 16 Sep, 2014 3.40.50.200 Assigned
4ne9B02 16 Sep, 2014 2.60.120.690 Assigned
4ne9C01 16 Sep, 2014 3.30.70.80 Assigned
4ne9P01 16 Sep, 2014 3.30.70.80 Assigned

UniProtKB Entries (5)

Accession Gene ID Taxon Description
Q8NBP7 PCSK9_HUMAN Homo sapiens Proprotein convertase subtilisin/kexin type 9
Q8NBP7 PCSK9_HUMAN Homo sapiens Proprotein convertase subtilisin/kexin type 9
Q8NBP7 PCSK9_HUMAN Homo sapiens Proprotein convertase subtilisin/kexin type 9
P01130 LDLR_HUMAN Homo sapiens Low-density lipoprotein receptor
Q8NBP7 PCSK9_HUMAN Homo sapiens Proprotein convertase subtilisin/kexin type 9