PDB Information

PDB4N4T
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMus musculus
Primary Citation
Structure-based design of 2-aminopyridine oxazolidinones as potent and selective tankyrase inhibitors.
Huang, H., Guzman-Perez, A., Acquaviva, L., Berry, V., Bregman, H., Dovey, J., Gunaydin, H., Huang, X., Huang, L., Saffran, D., Serafino, R., Schneider, S., Wilson, C., DiMauro, E.F.
ACS Med Chem Lett
HeaderTransferase/Transferase Inhibitor
Released2013-10-08
Resolution2.320
CATH Insert Date15 Dec, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2013 Chopped
B 16 Dec, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4n4tA00 20 Dec, 2013 3.90.228.10 Assigned
4n4tB00 20 Dec, 2013 3.90.228.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q6PFX9 TNKS1_MOUSE Mus musculus Poly [ADP-ribose] polymerase tankyrase-1
Q6PFX9 TNKS1_MOUSE Mus musculus Poly [ADP-ribose] polymerase tankyrase-1