PDB 4mvh

PDB Links
Overview

PDB Information

PDB	4MVH
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Design, Optimization, and Biological Evaluation of Novel Keto-Benzimidazoles as Potent and Selective Inhibitors of Phosphodiesterase 10A (PDE10A). Hu, E., Kunz, R.K., Chen, N., Rumfelt, S., Siegmund, A., Andrews, K., Chmait, S., Zhao, S., Davis, C., Chen, H., Lester-Zeiner, D., Ma, J., Biorn, C., Shi, J., Porter, A., Treanor, J., Allen, J.R. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-09-24
Resolution	2.500
CATH Insert Date	27 Oct, 2013

PDB Images (5)

Image of CATH 4mvh

4mvh

PDB 4mvh

Image of CATH 4mvhA

4mvhA

PDB Chain 4mvhA

Image of CATH 4mvhB

4mvhB

PDB Chain 4mvhB

Image of CATH 4mvhA00

4mvhA00

CATH Domain 4mvhA00

Image of CATH 4mvhB00

4mvhB00

CATH Domain 4mvhB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	28 Oct, 2013	Chopped
B	28 Oct, 2013	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4mvhA00	02 Nov, 2013	1.10.1300.10	Assigned
4mvhB00	02 Nov, 2013	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A