PDB 4msg

PDB Information

PDB4MSG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.
Hua, Z., Bregman, H., Buchanan, J.L., Chakka, N., Guzman-Perez, A., Gunaydin, H., Huang, X., Gu, Y., Berry, V., Liu, J., Teffera, Y., Huang, L., Egge, B., Emkey, R., Mullady, E.L., Schneider, S., Andrews, P.S., Acquaviva, L., Dovey, J., Mishra, A., Newcomb, J., Saffran, D., Serafino, R., Strathdee, C.A., Turci, S.M., Stanton, M., Wilson, C., Dimauro, E.F.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2013-09-18
Resolution1.800
CATH Insert Date05 Jan, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 06 Jan, 2014 Chopped
B 06 Jan, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4msgA00 09 Jan, 2014 3.90.228.10 Assigned
4msgB00 09 Jan, 2014 3.90.228.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O95271 TNKS1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-1
O95271 TNKS1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-1