PDB 4mk8

PDB Links
Overview

PDB Information

PDB	4MK8
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Hepatitis C virus
Primary Citation	Discovery of a Novel Series of Potent Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B. Schoenfeld, R.C., Bourdet, D.L., Brameld, K.A., Chin, E., de Vicente, J., Fung, A., Harris, S.F., Lee, E.K., Le Pogam, S., Leveque, V., Li, J., Lui, A.S., Najera, I., Rajyaguru, S., Sangi, M., Steiner, S., Talamas, F.X., Taygerly, J.P., Zhao, J. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2013-09-04
Resolution	2.090
CATH Insert Date	13 Oct, 2013

PDB Images (11)

Image of CATH 4mk8

4mk8

PDB 4mk8

Image of CATH 4mk8A

4mk8A

PDB Chain 4mk8A

Image of CATH 4mk8B

4mk8B

PDB Chain 4mk8B

Image of CATH 4mk8A01

4mk8A01

CATH Domain 4mk8A01

Image of CATH 4mk8A02

4mk8A02

CATH Domain 4mk8A02

Image of CATH 4mk8A03

4mk8A03

CATH Domain 4mk8A03

Image of CATH 4mk8A04

4mk8A04

CATH Domain 4mk8A04

Image of CATH 4mk8B01

4mk8B01

CATH Domain 4mk8B01

Image of CATH 4mk8B02

4mk8B02

CATH Domain 4mk8B02

Image of CATH 4mk8B03

4mk8B03

CATH Domain 4mk8B03

Image of CATH 4mk8B04

4mk8B04

CATH Domain 4mk8B04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	14 Oct, 2013	Chopped
B	14 Oct, 2013	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4mk8A01	17 Oct, 2013		Holding pen
4mk8A02	17 Oct, 2013		Holding pen
4mk8A03	17 Oct, 2013	3.30.70.270	Assigned
4mk8A04	17 Oct, 2013		Holding pen
4mk8B01	17 Oct, 2013		Holding pen
4mk8B02	17 Oct, 2013		Holding pen
4mk8B03	17 Oct, 2013	3.30.70.270	Assigned
4mk8B04	17 Oct, 2013		Holding pen

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P26663	POLG_HCVBK	Hepatitis C virus (isolate BK)	Genome polyprotein
P26663	POLG_HCVBK	Hepatitis C virus (isolate BK)	Genome polyprotein