PDB 4mf1

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Overview

PDB Information

PDB	4MF1
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK). Mackinnon, C.H., Lau, K., Burch, J.D., Chen, Y., Dines, J., Ding, X., Eigenbrot, C., Heifetz, A., Jaochico, A., Johnson, A., Kraemer, J., Kruger, S., Krulle, T.M., Liimatta, M., Ly, J., Maghames, R., Montalbetti, C.A., Ortwine, D.F., Perez-Fuertes, Y., Shia, S., Stein, D.B., Trani, G., Vaidya, D.G., Wang, X., Bromidge, S.M., Wu, L.C., Pei, Z. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2013-08-27
Resolution	2.110
CATH Insert Date	17 Nov, 2013

PDB Images (7)

Image of CATH 4mf1

4mf1

PDB 4mf1

Image of CATH 4mf1A

4mf1A

PDB Chain 4mf1A

Image of CATH 4mf1B

4mf1B

PDB Chain 4mf1B

Image of CATH 4mf1A01

4mf1A01

CATH Domain 4mf1A01

Image of CATH 4mf1A02

4mf1A02

CATH Domain 4mf1A02

Image of CATH 4mf1B01

4mf1B01

CATH Domain 4mf1B01

Image of CATH 4mf1B02

4mf1B02

CATH Domain 4mf1B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	18 Nov, 2013	Chopped
B	18 Nov, 2013	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4mf1A01	03 Dec, 2013	3.30.200.20	Assigned
4mf1A02	03 Dec, 2013	1.10.510.10	Assigned
4mf1B01	03 Dec, 2013	3.30.200.20	Assigned
4mf1B02	03 Dec, 2013	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q08881	ITK_HUMAN	Homo sapiens	Tyrosine-protein kinase ITK/TSK
Q08881	ITK_HUMAN	Homo sapiens	Tyrosine-protein kinase ITK/TSK