PDB 4mf1

PDB Information

PDB4MF1
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK).
Mackinnon, C.H., Lau, K., Burch, J.D., Chen, Y., Dines, J., Ding, X., Eigenbrot, C., Heifetz, A., Jaochico, A., Johnson, A., Kraemer, J., Kruger, S., Krulle, T.M., Liimatta, M., Ly, J., Maghames, R., Montalbetti, C.A., Ortwine, D.F., Perez-Fuertes, Y., Shia, S., Stein, D.B., Trani, G., Vaidya, D.G., Wang, X., Bromidge, S.M., Wu, L.C., Pei, Z.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2013-08-27
Resolution2.110
CATH Insert Date17 Nov, 2013

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 18 Nov, 2013 Chopped
B 18 Nov, 2013 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4mf1A01 03 Dec, 2013 3.30.200.20 Assigned
4mf1A02 03 Dec, 2013 1.10.510.10 Assigned
4mf1B01 03 Dec, 2013 3.30.200.20 Assigned
4mf1B02 03 Dec, 2013 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK