PDB 4mf0

PDB Information

PDB4MF0
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK).
Mackinnon, C.H., Lau, K., Burch, J.D., Chen, Y., Dines, J., Ding, X., Eigenbrot, C., Heifetz, A., Jaochico, A., Johnson, A., Kraemer, J., Kruger, S., Krulle, T.M., Liimatta, M., Ly, J., Maghames, R., Montalbetti, C.A., Ortwine, D.F., Perez-Fuertes, Y., Shia, S., Stein, D.B., Trani, G., Vaidya, D.G., Wang, X., Bromidge, S.M., Wu, L.C., Pei, Z.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2013-08-27
Resolution2.670
CATH Insert Date17 Nov, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 18 Nov, 2013 Chopped
B 18 Nov, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4mf0A00 03 Dec, 2013 1.10.510.10 Assigned
4mf0B00 03 Dec, 2013 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK
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