PDB 4mds

PDB Information

PDB4MDS
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceSARS coronavirus
Primary Citation
Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: Identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding.
Turlington, M., Chun, A., Tomar, S., Eggler, A., Grum-Tokars, V., Jacobs, J., Daniels, J.S., Dawson, E., Saldanha, A., Chase, P., Baez-Santos, Y.M., Lindsley, C.W., Hodder, P., Mesecar, A.D., Stauffer, S.R.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2013-08-23
Resolution1.600
CATH Insert Date06 Oct, 2013

PDB Images (5)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 07 Oct, 2013 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4mdsA01 10 Oct, 2013 2.40.10.10 Assigned
4mdsA02 10 Oct, 2013 2.40.10.10 Assigned
4mdsA03 10 Oct, 2013 1.10.1840.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P0C6U8 R1A_CVHSA Severe acute respiratory syndrome-related coronavirus Replicase polyprotein 1a
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