PDB Information

PDB4MDK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin.
Huang, H., Ceccarelli, D.F., Orlicky, S., St-Cyr, D.J., Ziemba, A., Garg, P., Plamondon, S., Auer, M., Sidhu, S., Marinier, A., Kleiger, G., Tyers, M., Sicheri, F.
Nat.Chem.Biol.
HeaderLigase/Ligase Inhibitor
Released2013-08-22
Resolution2.610
CATH Insert Date15 Dec, 2013

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2013 Chopped
B 16 Dec, 2013 Chopped
C 16 Dec, 2013 Chopped
D 16 Dec, 2013 Chopped
E 16 Dec, 2013 Chopped
F 16 Dec, 2013 Chopped
G 16 Dec, 2013 Chopped
H 16 Dec, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4mdkA00 20 Dec, 2013 3.10.110.10 Assigned
4mdkB00 20 Dec, 2013 3.10.110.10 Assigned
4mdkC00 20 Dec, 2013 3.10.110.10 Assigned
4mdkD00 20 Dec, 2013 3.10.110.10 Assigned
4mdkE00 20 Dec, 2013 3.10.20.90 Assigned
4mdkF00 20 Dec, 2013 3.10.20.90 Assigned
4mdkG00 20 Dec, 2013 3.10.20.90 Assigned
4mdkH00 20 Dec, 2013 3.10.20.90 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P49427 UB2R1_HUMAN Homo sapiens Ubiquitin-conjugating enzyme E2 R1
P49427 UB2R1_HUMAN Homo sapiens Ubiquitin-conjugating enzyme E2 R1
P0CG48 UBC_HUMAN Homo sapiens Polyubiquitin-C
P0CG48 UBC_HUMAN Homo sapiens Polyubiquitin-C
P0CG48 UBC_HUMAN Homo sapiens Polyubiquitin-C
P49427 UB2R1_HUMAN Homo sapiens Ubiquitin-conjugating enzyme E2 R1
P0CG48 UBC_HUMAN Homo sapiens Polyubiquitin-C
P49427 UB2R1_HUMAN Homo sapiens Ubiquitin-conjugating enzyme E2 R1