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PDB Information
| PDB | 4M22 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation |
K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.
Nature
|
| Header | Signaling Protein/Inhibitor |
| Released | 2013-08-05 |
| Resolution | 2.090 |
| CATH Insert Date | 01 Dec, 2013 |
PDB Images (7)
4m22A00
CATH Domain 4m22A00
4m22B00
CATH Domain 4m22B00
4m22C00
CATH Domain 4m22C00
PDB Chains (3)
| Chain ID | Date inserted into CATH | CATH Status |
| A | 02 Dec, 2013 | Chopped
|
| B | 02 Dec, 2013 | Chopped
|
| C | 02 Dec, 2013 | Chopped
|
CATH Domains (3)
UniProtKB Entries (3)
| Accession |
Gene ID |
Taxon |
Description |
| P01116 |
RASK_HUMAN |
Homo sapiens |
GTPase KRas |
| P01116 |
RASK_HUMAN |
Homo sapiens |
GTPase KRas |
| P01116 |
RASK_HUMAN |
Homo sapiens |
GTPase KRas |