PDB Information

PDB4M1C
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Crystal Structure Analysis of Fab-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Amyloid-Beta (1-40)
McCord, L.A., Liang, W., Farcasanu, M., Scherpelz, K., Meredith, S.C., Koide, S., Tang, W.J.
To be Published
HeaderHydrolase
Released2013-08-02
Resolution3.500
CATH Insert Date24 Aug, 2014

PDB Images (25)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 25 Aug, 2014 Chopped
B 25 Aug, 2014 Chopped
C 25 Aug, 2014 Chopped
D 25 Aug, 2014 Chopped
E 25 Aug, 2014 Chopped
F 25 Aug, 2014 Chopped
G 25 Aug, 2014 Rejected
H 25 Aug, 2014 Rejected

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
4m1cA01 27 Aug, 2014 3.30.830.10 Assigned
4m1cA02 27 Aug, 2014 3.30.830.10 Assigned
4m1cA03 27 Aug, 2014 3.30.830.10 Assigned
4m1cA04 27 Aug, 2014 3.30.830.10 Assigned
4m1cB01 27 Aug, 2014 3.30.830.10 Assigned
4m1cB02 27 Aug, 2014 3.30.830.10 Assigned
4m1cB03 27 Aug, 2014 3.30.830.10 Assigned
4m1cB04 27 Aug, 2014 3.30.830.10 Assigned
4m1cC01 27 Aug, 2014 2.60.40.10 Assigned
4m1cC02 27 Aug, 2014 2.60.40.10 Assigned
4m1cD01 27 Aug, 2014 2.60.40.10 Assigned
4m1cD02 27 Aug, 2014 2.60.40.10 Assigned
4m1cE01 27 Aug, 2014 2.60.40.10 Assigned
4m1cE02 27 Aug, 2014 2.60.40.10 Assigned
4m1cF01 27 Aug, 2014 2.60.40.10 Assigned
4m1cF02 27 Aug, 2014 2.60.40.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P05067 A4_HUMAN Homo sapiens Amyloid beta A4 protein
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme
P05067 A4_HUMAN Homo sapiens Amyloid beta A4 protein