×
Network disruptions
We have been experiencing disruptions on our local network which has affected the stability of these web pages.
We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.
PDB Information
| PDB | 4LYH |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation |
K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Ostrem, J.M., Peters, U., Sos, M.L., Wells, J.A., Shokat, K.M.
Nature
|
| Header | Signaling Protein/Inhibitor |
| Released | 2013-07-31 |
| Resolution | 1.370 |
| CATH Insert Date | 01 Dec, 2013 |
PDB Images (7)
4lyhA00
CATH Domain 4lyhA00
4lyhB00
CATH Domain 4lyhB00
4lyhC00
CATH Domain 4lyhC00
PDB Chains (3)
| Chain ID | Date inserted into CATH | CATH Status |
| A | 02 Dec, 2013 | Chopped
|
| B | 02 Dec, 2013 | Chopped
|
| C | 02 Dec, 2013 | Chopped
|
CATH Domains (3)
UniProtKB Entries (3)
| Accession |
Gene ID |
Taxon |
Description |
| P01116 |
RASK_HUMAN |
Homo sapiens |
GTPase KRas |
| P01116 |
RASK_HUMAN |
Homo sapiens |
GTPase KRas |
| P01116 |
RASK_HUMAN |
Homo sapiens |
GTPase KRas |