PDB 4lpb

PDB Information

PDB4LPB
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceStreptococcus pneumoniae
Primary Citation
Fragment-to-Hit-to-Lead Discovery of a Novel Pyridylurea Scaffold of ATP Competitive Dual Targeting Type II Topoisomerase Inhibiting Antibacterial Agents.
Basarab, G.S., Manchester, J.I., Bist, S., Boriack-Sjodin, P.A., Dangel, B., Illingworth, R., Sherer, B.A., Sriram, S., Uria-Nickelsen, M., Eakin, A.E.
J.Med.Chem.
HeaderIsomerase/Isomerase Inhibitor
Released2013-07-15
Resolution1.750
CATH Insert Date03 Nov, 2013

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 04 Nov, 2013 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4lpbA00 08 Nov, 2013 3.30.565.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q8DQB5 Q8DQB5_STRR6 Streptococcus pneumoniae R6 DNA topoisomerase 4 subunit B
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