PDB Information

PDB4LM1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
Recht, M.I., Sridhar, V., Badger, J., Bounaud, P.Y., Logan, C., Chie-Leon, B., Nienaber, V., Torres, F.E.
J Biomol Screen
HeaderHydrolase/Hydrolase Inhibitor
Released2013-07-09
Resolution1.600
CATH Insert Date09 Mar, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 10 Mar, 2014 Chopped
B 10 Mar, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4lm1A00 25 Apr, 2014 1.10.1300.10 Assigned
4lm1B00 25 Apr, 2014 1.10.1300.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9Y233 PDE10_HUMAN Homo sapiens cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233 PDE10_HUMAN Homo sapiens cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A