PDB 4leo

PDB Links
Overview

PDB Information

PDB	4LEO
Method	X-RAY DIFFRACTION
Host Organism	Cricetulus griseus
Gene Source	Mus musculus
Primary Citation	RG7116, a Therapeutic Antibody That Binds the Inactive HER3 Receptor and Is Optimized for Immune Effector Activation. Mirschberger, C., Schiller, C.B., Schraml, M., Dimoudis, N., Friess, T., Gerdes, C.A., Reiff, U., Lifke, V., Hoelzlwimmer, G., Kolm, I., Hopfner, K.P., Niederfellner, G., Bossenmaier, B. Cancer Res.
Header	Transferase/Immune System
Released	2013-06-26
Resolution	2.640
CATH Insert Date	04 Aug, 2013

PDB Images (12)

Image of CATH 4leo

4leo

PDB 4leo

Image of CATH 4leoA

4leoA

PDB Chain 4leoA

Image of CATH 4leoB

4leoB

PDB Chain 4leoB

Image of CATH 4leoC

4leoC

PDB Chain 4leoC

Image of CATH 4leoA01

4leoA01

CATH Domain 4leoA01

Image of CATH 4leoA02

4leoA02

CATH Domain 4leoA02

Image of CATH 4leoB01

4leoB01

CATH Domain 4leoB01

Image of CATH 4leoB02

4leoB02

CATH Domain 4leoB02

Image of CATH 4leoC01

4leoC01

CATH Domain 4leoC01

Image of CATH 4leoC02

4leoC02

CATH Domain 4leoC02

Image of CATH 4leoC03

4leoC03

CATH Domain 4leoC03

Image of CATH 4leoC04

4leoC04

CATH Domain 4leoC04

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	05 Aug, 2013	Chopped
B	05 Aug, 2013	Chopped
C	05 Aug, 2013	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4leoA01	14 Aug, 2013	2.60.40.10	Assigned
4leoA02	14 Aug, 2013	2.60.40.10	Assigned
4leoB01	14 Aug, 2013	2.60.40.10	Assigned
4leoB02	14 Aug, 2013	2.60.40.10	Assigned
4leoC01	07 Mar, 2014	3.80.20.20	Assigned
4leoC02	07 Mar, 2014	2.10.220.10	Assigned
4leoC03	07 Mar, 2014	3.80.20.20	Assigned
4leoC04	07 Mar, 2014	2.10.220.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P21860	ERBB3_HUMAN	Homo sapiens	Receptor tyrosine-protein kinase erbB-3