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PDB Information
| PDB | 4L9P |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Aspergillus fumigatus |
| Primary Citation |
Crystal structures of the fungal pathogen Aspergillus fumigatus protein farnesyltransferase complexed with substrates and inhibitors reveal features for antifungal drug design.
Mabanglo, M.F., Hast, M.A., Lubock, N.B., Hellinga, H.W., Beese, L.S.
Protein Sci.
|
| Header | Transferase |
| Released | 2013-06-18 |
| Resolution | 1.450 |
| CATH Insert Date | 05 Jan, 2014 |
PDB Images (6)
4l9pA00
CATH Domain 4l9pA00
4l9pB00
CATH Domain 4l9pB00
PDB Chains (3)
| Chain ID | Date inserted into CATH | CATH Status |
| A | 06 Jan, 2014 | Chopped
|
| B | 06 Jan, 2014 | Chopped
|
| C | 06 Jan, 2014 | Rejected
|
CATH Domains (2)
UniProtKB Entries (2)
| Accession |
Gene ID |
Taxon |
Description |
| Q4WP27 |
Q4WP27_ASPFU |
Aspergillus fumigatus Af293 |
CaaX farnesyltransferase alpha subunit Ram2 |
| Q4WPS9 |
Q4WPS9_ASPFU |
Aspergillus fumigatus Af293 |
Protein farnesyltransferase subunit beta |