PDB Information

PDB4L7S
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Identification of a Novel and Selective Series of Itk Inhibitors via a Template-Hopping Strategy.
Alder, C.M., Ambler, M., Campbell, A.J., Champigny, A.C., Deakin, A.M., Harling, J.D., Harris, C.A., Longstaff, T., Lynn, S., Maxwell, A.C., Mooney, C.J., Scullion, C., Singh, O.M., Smith, I.E., Somers, D.O., Tame, C.J., Wayne, G., Wilson, C., Woolven, J.M.
ACS Med Chem Lett
HeaderTransferase/Transferase Inhibitor
Released2013-06-14
Resolution2.030
CATH Insert Date02 Feb, 2014

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Feb, 2014 Chopped
B 03 Feb, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4l7sA01 07 Mar, 2014 3.30.200.20 Assigned
4l7sA02 07 Mar, 2014 1.10.510.10 Assigned
4l7sB01 07 Mar, 2014 3.30.200.20 Assigned
4l7sB02 07 Mar, 2014 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK