PDB 4l6s

PDB Links
Overview

PDB Information

PDB	4L6S
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of novel benzo[b][1,4]oxazin-3(4H)-ones as poly(ADP-ribose)polymerase inhibitors Gangloff, A.R., Brown, J., de Jong, R., Dougan, D.R., Grimshaw, C.E., Hixon, M., Jennings, A., Kamran, R., Kiryanov, A., O'Connell, S., Taylor, E., Vu, P. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2013-06-12
Resolution	2.200
CATH Insert Date	01 Sep, 2013

PDB Images (7)

Image of CATH 4l6s

4l6s

PDB 4l6s

Image of CATH 4l6sA

4l6sA

PDB Chain 4l6sA

Image of CATH 4l6sB

4l6sB

PDB Chain 4l6sB

Image of CATH 4l6sA01

4l6sA01

CATH Domain 4l6sA01

Image of CATH 4l6sA02

4l6sA02

CATH Domain 4l6sA02

Image of CATH 4l6sB01

4l6sB01

CATH Domain 4l6sB01

Image of CATH 4l6sB02

4l6sB02

CATH Domain 4l6sB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	02 Sep, 2013	Chopped
B	02 Sep, 2013	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4l6sA01	04 Sep, 2013	1.20.142.10	Assigned
4l6sA02	04 Sep, 2013	3.90.228.10	Assigned
4l6sB01	03 Sep, 2013	1.20.142.10	Assigned
4l6sB02	03 Sep, 2013	3.90.228.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P09874	PARP1_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase 1
P09874	PARP1_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase 1