PDB 4kzc

PDB Links
Overview

PDB Information

PDB	4KZC
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Structure guided optimization of a fragment hit to imidazopyridine inhibitors of PI3K. Pecchi, S., Ni, Z.J., Han, W., Smith, A., Lan, J., Burger, M., Merritt, H., Wiesmann, M., Chan, J., Kaufman, S., Knapp, M.S., Janssen, J., Huh, K., Voliva, C.F. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2013-05-29
Resolution	3.250
CATH Insert Date	04 Aug, 2013

PDB Images (7)

Image of CATH 4kzc

4kzc

PDB 4kzc

Image of CATH 4kzcA

4kzcA

PDB Chain 4kzcA

Image of CATH 4kzcA01

4kzcA01

CATH Domain 4kzcA01

Image of CATH 4kzcA02

4kzcA02

CATH Domain 4kzcA02

Image of CATH 4kzcA03

4kzcA03

CATH Domain 4kzcA03

Image of CATH 4kzcA04

4kzcA04

CATH Domain 4kzcA04

Image of CATH 4kzcA05

4kzcA05

CATH Domain 4kzcA05

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	05 Aug, 2013	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4kzcA01	14 Aug, 2013	3.10.20.90	Assigned
4kzcA02	14 Aug, 2013	2.60.40.150	Assigned
4kzcA03	14 Aug, 2013	1.25.40.70	Assigned
4kzcA04	14 Aug, 2013	3.30.1010.10	Assigned
4kzcA05	14 Aug, 2013	1.10.1070.11	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P48736	PK3CG_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform