PDB 4kz0

PDB Links
Overview

PDB Information

PDB	4KZ0
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Structure guided optimization of a fragment hit to imidazopyridine inhibitors of PI3K. Pecchi, S., Ni, Z.J., Han, W., Smith, A., Lan, J., Burger, M., Merritt, H., Wiesmann, M., Chan, J., Kaufman, S., Knapp, M.S., Janssen, J., Huh, K., Voliva, C.F. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2013-05-29
Resolution	2.870
CATH Insert Date	04 Aug, 2013

PDB Images (7)

Image of CATH 4kz0

4kz0

PDB 4kz0

Image of CATH 4kz0A

4kz0A

PDB Chain 4kz0A

Image of CATH 4kz0A01

4kz0A01

CATH Domain 4kz0A01

Image of CATH 4kz0A02

4kz0A02

CATH Domain 4kz0A02

Image of CATH 4kz0A03

4kz0A03

CATH Domain 4kz0A03

Image of CATH 4kz0A04

4kz0A04

CATH Domain 4kz0A04

Image of CATH 4kz0A05

4kz0A05

CATH Domain 4kz0A05

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	05 Aug, 2013	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4kz0A01	14 Aug, 2013	3.10.20.90	Assigned
4kz0A02	14 Aug, 2013	2.60.40.150	Assigned
4kz0A03	14 Aug, 2013	1.25.40.70	Assigned
4kz0A04	14 Aug, 2013	3.30.1010.10	Assigned
4kz0A05	14 Aug, 2013	1.10.1070.11	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P48736	PK3CG_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform