PDB 4kya

PDB Information

PDB4KYA
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceToxoplasma gondii
Primary Citation
Discovery of potent and selective inhibitors of Toxoplasma gondii thymidylate synthase for opportunistic infections.
Zaware, N., Sharma, H., Yang, J., Devambatla, R.K., Queener, S.F., Anderson, K.S., Gangjee, A.
ACS Med Chem Lett
HeaderOxidoreductase, Transferase/Inhibitor
Released2013-05-28
Resolution3.260
CATH Insert Date24 Aug, 2014

PDB Images (33)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 25 Aug, 2014 Chopped
B 25 Aug, 2014 Chopped
C 25 Aug, 2014 Chopped
D 25 Aug, 2014 Chopped
E 25 Aug, 2014 Chopped
F 25 Aug, 2014 Chopped
G 25 Aug, 2014 Chopped
H 25 Aug, 2014 Chopped

CATH Domains (24)

Domain ID Date inserted into CATH Superfamily CATH Status
4kyaA01 27 Aug, 2014 3.40.430.10 Assigned
4kyaA02 27 Aug, 2014 Holding pen
4kyaA03 27 Aug, 2014 3.30.572.10 Assigned
4kyaB01 28 Aug, 2014 3.40.430.10 Assigned
4kyaB02 28 Aug, 2014 Holding pen
4kyaB03 28 Aug, 2014 3.30.572.10 Assigned
4kyaC01 27 Aug, 2014 3.40.430.10 Assigned
4kyaC02 27 Aug, 2014 Holding pen
4kyaC03 27 Aug, 2014 3.30.572.10 Assigned
4kyaD01 27 Aug, 2014 3.40.430.10 Assigned
4kyaD02 27 Aug, 2014 Holding pen
4kyaD03 27 Aug, 2014 3.30.572.10 Assigned
4kyaE01 27 Aug, 2014 3.40.430.10 Assigned
4kyaE02 27 Aug, 2014 Holding pen
4kyaE03 27 Aug, 2014 3.30.572.10 Assigned
4kyaF01 27 Aug, 2014 3.40.430.10 Assigned
4kyaF02 27 Aug, 2014 Holding pen
4kyaF03 27 Aug, 2014 3.30.572.10 Assigned
4kyaG01 28 Aug, 2014 3.40.430.10 Assigned
4kyaG02 28 Aug, 2014 Holding pen
4kyaG03 28 Aug, 2014 3.30.572.10 Assigned
4kyaH01 27 Aug, 2014 3.40.430.10 Assigned
4kyaH02 27 Aug, 2014 Holding pen
4kyaH03 27 Aug, 2014 3.30.572.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q07422 DRTS_TOXGO Toxoplasma gondii Bifunctional dihydrofolate reductase-thymidylate synthase
Q07422 DRTS_TOXGO Toxoplasma gondii Bifunctional dihydrofolate reductase-thymidylate synthase
Q07422 DRTS_TOXGO Toxoplasma gondii Bifunctional dihydrofolate reductase-thymidylate synthase
Q07422 DRTS_TOXGO Toxoplasma gondii Bifunctional dihydrofolate reductase-thymidylate synthase
Q07422 DRTS_TOXGO Toxoplasma gondii Bifunctional dihydrofolate reductase-thymidylate synthase
Q07422 DRTS_TOXGO Toxoplasma gondii Bifunctional dihydrofolate reductase-thymidylate synthase
Q07422 DRTS_TOXGO Toxoplasma gondii Bifunctional dihydrofolate reductase-thymidylate synthase
Q07422 DRTS_TOXGO Toxoplasma gondii Bifunctional dihydrofolate reductase-thymidylate synthase
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