PDB 4kpw

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Overview

PDB Information

PDB	4KPW
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Hotspots in an obligate homodimeric anticancer target. Structural and functional effects of interfacial mutations in human thymidylate synthase. Salo-Ahen, O.M., Tochowicz, A., Pozzi, C., Cardinale, D., Ferrari, S., Boum, Y., Mangani, S., Stroud, R.M., Saxena, P., Myllykallio, H., Costi, M.P., Ponterini, G., Wade, R.C. J.Med.Chem.
Header	Transferase
Released	2013-05-14
Resolution	2.030
CATH Insert Date	18 May, 2014

PDB Images (3)

Image of CATH 4kpw

4kpw

PDB 4kpw

Image of CATH 4kpwA

4kpwA

PDB Chain 4kpwA

Image of CATH 4kpwA00

4kpwA00

CATH Domain 4kpwA00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	19 May, 2014	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4kpwA00	21 May, 2014	3.30.572.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P04818	TYSY_HUMAN	Homo sapiens	Thymidylate synthase