PDB 4knb

PDB Information

PDB4KNB
MethodX-RAY DIFFRACTION
Host OrganismInsecta
Gene SourceHomo sapiens
Primary Citation
Novel 6-aminofuro[3,2-c]pyridines as potent, orally efficacious inhibitors of cMET and RON kinases.
Steinig, A.G., Li, A.H., Wang, J., Chen, X., Dong, H., Ferraro, C., Jin, M., Kadalbajoo, M., Kleinberg, A., Stolz, K.M., Tavares-Greco, P.A., Wang, T., Albertella, M.R., Peng, Y., Crew, L., Kahler, J., Kan, J., Schulz, R., Cooke, A., Bittner, M., Turton, R.W., Franklin, M., Gokhale, P., Landfair, D., Mantis, C., Workman, J., Wild, R., Pachter, J., Epstein, D., Mulvihill, M.J.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2013-05-09
Resolution2.400
CATH Insert Date04 May, 2014

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 May, 2014 Chopped
B 05 May, 2014 Chopped
C 05 May, 2014 Chopped
D 05 May, 2014 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4knbA01 09 May, 2014 3.30.200.20 Assigned
4knbA02 09 May, 2014 1.10.510.10 Assigned
4knbB01 09 May, 2014 3.30.200.20 Assigned
4knbB02 09 May, 2014 1.10.510.10 Assigned
4knbC01 08 May, 2014 3.30.200.20 Assigned
4knbC02 08 May, 2014 1.10.510.10 Assigned
4knbD01 09 May, 2014 3.30.200.20 Assigned
4knbD02 09 May, 2014 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P08581 MET_HUMAN Homo sapiens Hepatocyte growth factor receptor
P08581 MET_HUMAN Homo sapiens Hepatocyte growth factor receptor
P08581 MET_HUMAN Homo sapiens Hepatocyte growth factor receptor
P08581 MET_HUMAN Homo sapiens Hepatocyte growth factor receptor
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