PDB Information

PDB4KL1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness.
Lolicato, M., Bucchi, A., Arrigoni, C., Zucca, S., Nardini, M., Schroeder, I., Simmons, K., Aquila, M., DiFrancesco, D., Bolognesi, M., Schwede, F., Kashin, D., Fishwick, C.W., Johnson, A.P., Thiel, G., Moroni, A.
Nat.Chem.Biol.
HeaderProtein Transport
Released2013-05-07
Resolution2.700
CATH Insert Date04 May, 2014

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 May, 2014 Chopped
B 05 May, 2014 Chopped
C 05 May, 2014 Chopped
D 05 May, 2014 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4kl1A01 08 May, 2014 1.10.287.630 Assigned
4kl1A02 08 May, 2014 2.60.120.10 Assigned
4kl1B01 09 May, 2014 1.10.287.630 Assigned
4kl1B02 09 May, 2014 2.60.120.10 Assigned
4kl1C01 09 May, 2014 1.10.287.630 Assigned
4kl1C02 09 May, 2014 2.60.120.10 Assigned
4kl1D01 09 May, 2014 1.10.287.630 Assigned
4kl1D02 09 May, 2014 2.60.120.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9Y3Q4 HCN4_HUMAN Homo sapiens Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Q9Y3Q4 HCN4_HUMAN Homo sapiens Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Q9Y3Q4 HCN4_HUMAN Homo sapiens Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Q9Y3Q4 HCN4_HUMAN Homo sapiens Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4