PDB 4khm

PDB Information

PDB4KHM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus subtype 1a
Primary Citation
Discovery of a Potent Boronic Acid Derived Inhibitor of the HCV RNA-Dependent RNA Polymerase.
Maynard, A., Crosby, R.M., Ellis, B., Hamatake, R., Hong, Z., Johns, B.A., Kahler, K.M., Koble, C., Leivers, A., Leivers, M.R., Mathis, A., Peat, A.J., Pouliot, J.J., Roberts, C.D., Samano, V., Schmidt, R.M., Smith, G.K., Spaltenstein, A., Stewart, E.L., Thommes, P., Turner, E.M., Voitenleitner, C., Walker, J.T., Waitt, G., Weatherhead, J., Weaver, K., Williams, S., Wright, L., Xiong, Z.Z., Haigh, D., Shotwell, J.B.
J.Med.Chem.
HeaderReplication/Replication Inhibitor
Released2013-04-30
Resolution1.700
CATH Insert Date07 Jul, 2013

PDB Images (11)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4khmA01 08 Oct, 2013 Holding pen
4khmA02 08 Oct, 2013 Holding pen
4khmA03 08 Oct, 2013 3.30.70.270 Assigned
4khmA04 08 Oct, 2013 Holding pen
4khmB01 08 Oct, 2013 Holding pen
4khmB02 08 Oct, 2013 Holding pen
4khmB03 08 Oct, 2013 3.30.70.270 Assigned
4khmB04 08 Oct, 2013 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
B1PPP0 B1PPP0_9HEPC Hepatitis C virus subtype 1a Genome polyprotein
B1PPP0 B1PPP0_9HEPC Hepatitis C virus subtype 1a Genome polyprotein