PDB 4jwr

PDB Links
Overview

PDB Information

PDB	4JWR
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Rational Design and Binding Mode Duality of MDM2-p53 Inhibitors. Gonzalez-Lopez de Turiso, F., Sun, D., Rew, Y., Bartberger, M.D., Beck, H.P., Canon, J., Chen, A., Chow, D., Correll, T.L., Huang, X., Julian, L.D., Kayser, F., Lo, M.C., Long, A.M., McMinn, D., Oliner, J.D., Osgood, T., Powers, J.P., Saiki, A.Y., Schneider, S., Shaffer, P., Xiao, S.H., Yakowec, P., Yan, X., Ye, Q., Yu, D., Zhao, X., Zhou, J., Medina, J.C., Olson, S.H. J.Med.Chem.
Header	Ligase/Ligase Inhibitor
Released	2013-03-27
Resolution	2.350
CATH Insert Date	07 Jul, 2013

PDB Images (7)

Image of CATH 4jwr

4jwr

PDB 4jwr

Image of CATH 4jwrA

4jwrA

PDB Chain 4jwrA

Image of CATH 4jwrB

4jwrB

PDB Chain 4jwrB

Image of CATH 4jwrC

4jwrC

PDB Chain 4jwrC

Image of CATH 4jwrA00

4jwrA00

CATH Domain 4jwrA00

Image of CATH 4jwrB00

4jwrB00

CATH Domain 4jwrB00

Image of CATH 4jwrC00

4jwrC00

CATH Domain 4jwrC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	08 Jul, 2013	Chopped
B	08 Jul, 2013	Chopped
C	08 Jul, 2013	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4jwrA00	09 Aug, 2013	1.10.245.10	Assigned
4jwrB00	09 Aug, 2013	1.10.245.10	Assigned
4jwrC00	09 Aug, 2013	1.10.245.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
Q00987	MDM2_HUMAN	Homo sapiens	E3 ubiquitin-protein ligase Mdm2
Q00987	MDM2_HUMAN	Homo sapiens	E3 ubiquitin-protein ligase Mdm2
Q00987	MDM2_HUMAN	Homo sapiens	E3 ubiquitin-protein ligase Mdm2