PDB 4jv8

PDB Information

PDB4JV8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Small molecule inhibition of the KRAS PDEd interaction impairs oncogenic KRAS signalling
Zimmermann, G., Papke, B., Ismail, S., Vartak, N., Chandra, A., Hoffmann, M., Hahn, S.A., Triola, G., Wittinghofer, A., Bastiaens, P.I., Waldmann, H.
Nature
HeaderProtein Binding/Inhibitor
Released2013-03-25
Resolution1.450
CATH Insert Date07 Jul, 2013

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
B 08 Jul, 2013 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4jv8B00 09 Aug, 2013 2.70.50.40 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O43924 PDE6D_HUMAN Homo sapiens Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta