PDB 4jrg

PDB Information

PDB4JRG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceXenopus laevis
Primary Citation
Discovery of RG7388, a Potent and Selective p53-MDM2 Inhibitor in Clinical Development.
Ding, Q., Zhang, Z., Liu, J.J., Jiang, N., Zhang, J., Ross, T.M., Chu, X.J., Bartkovitz, D., Podlaski, F., Janson, C., Tovar, C., Filipovic, Z.M., Higgins, B., Glenn, K., Packman, K., Vassilev, L.T., Graves, B.
J.Med.Chem.
HeaderLigase/Ligase Inhibitor
Released2013-03-21
Resolution1.900
CATH Insert Date04 Aug, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Aug, 2013 Chopped
B 05 Aug, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4jrgA00 14 Aug, 2013 1.10.245.10 Assigned
4jrgB00 14 Aug, 2013 1.10.245.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P56273 MDM2_XENLA Xenopus laevis E3 ubiquitin-protein ligase Mdm2
P56273 MDM2_XENLA Xenopus laevis E3 ubiquitin-protein ligase Mdm2