PDB 4jju

PDB Information

PDB4JJU
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus
Primary Citation
Structure-based design of novel HCV NS5B thumb pocket 2 allosteric inhibitors with submicromolar gt1 replicon potency: Discovery of a quinazolinone chemotype.
Beaulieu, P.L., Coulombe, R., Duan, J., Fazal, G., Godbout, C., Hucke, O., Jakalian, A., Joly, M.A., Lepage, O., Llinas-Brunet, M., Naud, J., Poirier, M., Rioux, N., Thavonekham, B., Kukolj, G., Stammers, T.A.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2013-03-08
Resolution1.910
CATH Insert Date07 Jul, 2013

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4jjuA01 08 Oct, 2013 Holding pen
4jjuA02 08 Oct, 2013 Holding pen
4jjuB01 08 Oct, 2013 Holding pen
4jjuB02 08 Oct, 2013 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O92972 POLG_HCVJ4 Hepatitis C virus isolate HC-J4 Genome polyprotein
O92972 POLG_HCVJ4 Hepatitis C virus isolate HC-J4 Genome polyprotein
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