PDB 4ja8

PDB Information

PDB4JA8
MethodX-RAY DIFFRACTION
Host Organism
Gene SourceHomo sapiens
Primary Citation
Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation.
Wang, F., Travins, J., DeLaBarre, B., Penard-Lacronique, V., Schalm, S., Hansen, E., Straley, K., Kernytsky, A., Liu, W., Gliser, C., Yang, H., Gross, S., Artin, E., Saada, V., Mylonas, E., Quivoron, C., Popovici-Muller, J., Saunders, J.O., Salituro, F.G., Yan, S., Murray, S., Wei, W., Gao, Y., Dang, L., Dorsch, M., Agresta, S., Schenkein, D.P., Biller, S.A., Su, S.M., de Botton, S., Yen, K.E.
Science
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2013-02-18
Resolution1.550
CATH Insert Date07 Jul, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4ja8A00 09 Aug, 2013 3.40.718.10 Assigned
4ja8B00 09 Aug, 2013 3.40.718.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P48735 IDHP_HUMAN Homo sapiens Isocitrate dehydrogenase [NADP], mitochondrial
P48735 IDHP_HUMAN Homo sapiens Isocitrate dehydrogenase [NADP], mitochondrial