PDB Information

PDB4IZ5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK.
Mace, P.D., Wallez, Y., Egger, M.F., Dobaczewska, M.K., Robinson, H., Pasquale, E.B., Riedl, S.J.
Nat Commun
HeaderTransferase
Released2013-01-29
Resolution3.190
CATH Insert Date07 Jul, 2013

PDB Images (21)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped
C 08 Jul, 2013 Chopped
D 08 Jul, 2013 Chopped
E 08 Jul, 2013 Chopped
F 08 Jul, 2013 Chopped
G 08 Jul, 2013 Chopped
H 08 Jul, 2013 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
4iz5A01 09 Aug, 2013 3.30.200.20 Assigned
4iz5A02 09 Aug, 2013 1.10.510.10 Assigned
4iz5B01 09 Aug, 2013 3.30.200.20 Assigned
4iz5B02 09 Aug, 2013 1.10.510.10 Assigned
4iz5C01 09 Aug, 2013 3.30.200.20 Assigned
4iz5C02 09 Aug, 2013 1.10.510.10 Assigned
4iz5D01 09 Aug, 2013 3.30.200.20 Assigned
4iz5D02 09 Aug, 2013 1.10.510.10 Assigned
4iz5E00 28 Aug, 2013 1.10.533.10 Assigned
4iz5F00 28 Aug, 2013 1.10.533.10 Assigned
4iz5G00 28 Aug, 2013 1.10.533.10 Assigned
4iz5H00 28 Aug, 2013 1.10.533.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q15121 PEA15_HUMAN Homo sapiens Astrocytic phosphoprotein PEA-15
P28482 MK01_HUMAN Homo sapiens Mitogen-activated protein kinase 1
P28482 MK01_HUMAN Homo sapiens Mitogen-activated protein kinase 1
P28482 MK01_HUMAN Homo sapiens Mitogen-activated protein kinase 1
P28482 MK01_HUMAN Homo sapiens Mitogen-activated protein kinase 1
Q15121 PEA15_HUMAN Homo sapiens Astrocytic phosphoprotein PEA-15
Q15121 PEA15_HUMAN Homo sapiens Astrocytic phosphoprotein PEA-15
Q15121 PEA15_HUMAN Homo sapiens Astrocytic phosphoprotein PEA-15