PDB Information

PDB4ISU
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Studies on an (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist IKM-159: asymmetric synthesis, neuroactivity, and structural characterization.
Juknaite, L., Sugamata, Y., Tokiwa, K., Ishikawa, Y., Takamizawa, S., Eng, A., Sakai, R., Pickering, D.S., Frydenvang, K., Swanson, G.T., Kastrup, J.S., Oikawa, M.
J.Med.Chem.
HeaderMembrane Protein/Antagonist
Released2013-01-17
Resolution2.300
CATH Insert Date28 Mar, 2013

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2013 Chopped
B 28 Mar, 2013 Chopped
C 28 Mar, 2013 Chopped
D 28 Mar, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4isuA01 10 Apr, 2013 3.40.190.10 Assigned
4isuA02 10 Apr, 2013 3.40.190.10 Assigned
4isuB01 10 Apr, 2013 3.40.190.10 Assigned
4isuB02 10 Apr, 2013 3.40.190.10 Assigned
4isuC01 10 Apr, 2013 3.40.190.10 Assigned
4isuC02 10 Apr, 2013 3.40.190.10 Assigned
4isuD01 10 Apr, 2013 3.40.190.10 Assigned
4isuD02 10 Apr, 2013 3.40.190.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P19491 GRIA2_RAT Rattus norvegicus Glutamate receptor 2
P19491 GRIA2_RAT Rattus norvegicus Glutamate receptor 2
P19491 GRIA2_RAT Rattus norvegicus Glutamate receptor 2
P19491 GRIA2_RAT Rattus norvegicus Glutamate receptor 2