PDB Information

PDB4ISH
MethodX-RAY DIFFRACTION
Host OrganismCricetinae
Gene SourceHomo sapiens
Primary Citation
Discovery and gram-scale synthesis of BMS-593214, a potent, selective FVIIa inhibitor.
Priestley, E.S., De Lucca, I., Zhou, J., Zhou, J., Saiah, E., Stanton, R., Robinson, L., Luettgen, J.M., Wei, A., Wen, X., Knabb, R.M., Wong, P.C., Wexler, R.R.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2013-01-16
Resolution1.820
CATH Insert Date28 Mar, 2013

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
H 28 Mar, 2013 Chopped
L 28 Mar, 2013 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4ishH01 10 Apr, 2013 2.40.10.10 Assigned
4ishH02 10 Apr, 2013 2.40.10.10 Assigned
4ishL00 10 Apr, 2013 2.10.25.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII