PDB 4inr

PDB Links
Overview

PDB Information

PDB	4INR
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites. Geurink, P.P., van der Linden, W.A., Mirabella, A.C., Gallastegui, N., de Bruin, G., Blom, A.E., Voges, M.J., Mock, E.D., Florea, B.I., van der Marel, G.A., Driessen, C., van der Stelt, M., Groll, M., Overkleeft, H.S., Kisselev, A.F. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-01-06
Resolution	2.700
CATH Insert Date	03 Feb, 2013

PDB Images (57)

4inr

PDB 4inr

4inra

PDB Chain 4inra

4inrA

PDB Chain 4inrA

4inrb

PDB Chain 4inrb

4inrB

PDB Chain 4inrB

4inrC

PDB Chain 4inrC

4inrD

PDB Chain 4inrD

4inrE

PDB Chain 4inrE

4inrF

PDB Chain 4inrF

4inrG

PDB Chain 4inrG

4inrH

PDB Chain 4inrH

4inrI

PDB Chain 4inrI

4inrJ

PDB Chain 4inrJ

4inrK

PDB Chain 4inrK

4inrL

PDB Chain 4inrL

4inrM

PDB Chain 4inrM

4inrN

PDB Chain 4inrN

4inrO

PDB Chain 4inrO

4inrP

PDB Chain 4inrP

4inrQ

PDB Chain 4inrQ

4inrR

PDB Chain 4inrR

4inrS

PDB Chain 4inrS

4inrT

PDB Chain 4inrT

4inrU

PDB Chain 4inrU

4inrV

PDB Chain 4inrV

4inrW

PDB Chain 4inrW

4inrX

PDB Chain 4inrX

4inrY

PDB Chain 4inrY

4inrZ

PDB Chain 4inrZ

4inra00

CATH Domain 4inra00

4inrA00

CATH Domain 4inrA00

4inrb00

CATH Domain 4inrb00

4inrB00

CATH Domain 4inrB00

4inrC00

CATH Domain 4inrC00

4inrD00

CATH Domain 4inrD00

4inrE00

CATH Domain 4inrE00

4inrF00

CATH Domain 4inrF00

4inrG00

CATH Domain 4inrG00

4inrH00

CATH Domain 4inrH00

4inrI00

CATH Domain 4inrI00

4inrJ00

CATH Domain 4inrJ00

4inrK00

CATH Domain 4inrK00

4inrL00

CATH Domain 4inrL00

4inrM00

CATH Domain 4inrM00

4inrN00

CATH Domain 4inrN00

4inrO00

CATH Domain 4inrO00

4inrP00

CATH Domain 4inrP00

4inrQ00

CATH Domain 4inrQ00

4inrR00

CATH Domain 4inrR00

4inrS00

CATH Domain 4inrS00

4inrT00

CATH Domain 4inrT00

4inrU00

CATH Domain 4inrU00

4inrV00

CATH Domain 4inrV00

4inrW00

CATH Domain 4inrW00

4inrX00

CATH Domain 4inrX00

4inrY00

CATH Domain 4inrY00

4inrZ00

CATH Domain 4inrZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	04 Feb, 2013	Chopped
A	04 Feb, 2013	Chopped
b	04 Feb, 2013	Chopped
B	04 Feb, 2013	Chopped
C	04 Feb, 2013	Chopped
D	04 Feb, 2013	Chopped
E	04 Feb, 2013	Chopped
F	04 Feb, 2013	Chopped
G	04 Feb, 2013	Chopped
H	04 Feb, 2013	Chopped
I	04 Feb, 2013	Chopped
J	04 Feb, 2013	Chopped
K	04 Feb, 2013	Chopped
L	04 Feb, 2013	Chopped
M	04 Feb, 2013	Chopped
N	04 Feb, 2013	Chopped
O	04 Feb, 2013	Chopped
P	04 Feb, 2013	Chopped
Q	04 Feb, 2013	Chopped
R	04 Feb, 2013	Chopped
S	04 Feb, 2013	Chopped
T	04 Feb, 2013	Chopped
U	04 Feb, 2013	Chopped
V	04 Feb, 2013	Chopped
W	04 Feb, 2013	Chopped
X	04 Feb, 2013	Chopped
Y	04 Feb, 2013	Chopped
Z	04 Feb, 2013	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4inra00	11 Feb, 2013	3.60.20.10	Assigned
4inrA00	11 Feb, 2013	3.60.20.10	Assigned
4inrb00	11 Feb, 2013	3.60.20.10	Assigned
4inrB00	11 Feb, 2013	3.60.20.10	Assigned
4inrC00	11 Feb, 2013	3.60.20.10	Assigned
4inrD00	11 Feb, 2013	3.60.20.10	Assigned
4inrE00	11 Feb, 2013	3.60.20.10	Assigned
4inrF00	11 Feb, 2013	3.60.20.10	Assigned
4inrG00	11 Feb, 2013	3.60.20.10	Assigned
4inrH00	11 Feb, 2013	3.60.20.10	Assigned
4inrI00	11 Feb, 2013	3.60.20.10	Assigned
4inrJ00	11 Feb, 2013	3.60.20.10	Assigned
4inrK00	11 Feb, 2013	3.60.20.10	Assigned
4inrL00	11 Feb, 2013	3.60.20.10	Assigned
4inrM00	11 Feb, 2013	3.60.20.10	Assigned
4inrN00	11 Feb, 2013	3.60.20.10	Assigned
4inrO00	11 Feb, 2013	3.60.20.10	Assigned
4inrP00	11 Feb, 2013	3.60.20.10	Assigned
4inrQ00	11 Feb, 2013	3.60.20.10	Assigned
4inrR00	11 Feb, 2013	3.60.20.10	Assigned
4inrS00	11 Feb, 2013	3.60.20.10	Assigned
4inrT00	11 Feb, 2013	3.60.20.10	Assigned
4inrU00	11 Feb, 2013	3.60.20.10	Assigned
4inrV00	11 Feb, 2013	3.60.20.10	Assigned
4inrW00	11 Feb, 2013	3.60.20.10	Assigned
4inrX00	11 Feb, 2013	3.60.20.10	Assigned
4inrY00	11 Feb, 2013	3.60.20.10	Assigned
4inrZ00	11 Feb, 2013	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5