PDB 4ijv

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Overview

PDB Information

PDB	4IJV
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Optimization of 1,2,4-Triazolopyridines as Inhibitors of Human 11 beta-Hydroxysteroid Dehydrogenase Type 1 (11 beta-HSD-1). Li, J., Kennedy, L.J., Wang, H., Li, J.J., Walker, S.J., Hong, Z., O'Connor, S.P., Nayeem, A., Camac, D.M., Morin, P.E., Sheriff, S., Wang, M., Harper, T., Golla, R., Seethala, R., Harrity, T., Ponticiello, R.P., Morgan, N.N., Taylor, J.R., Zebo, R., Gordon, D.A., Robl, J.A. ACS Med Chem Lett
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2012-12-23
Resolution	2.350
CATH Insert Date	29 Jun, 2014

PDB Images (9)

Image of CATH 4ijv

4ijv

PDB 4ijv

Image of CATH 4ijvA

4ijvA

PDB Chain 4ijvA

Image of CATH 4ijvB

4ijvB

PDB Chain 4ijvB

Image of CATH 4ijvD

4ijvD

PDB Chain 4ijvD

Image of CATH 4ijvE

4ijvE

PDB Chain 4ijvE

Image of CATH 4ijvA00

4ijvA00

CATH Domain 4ijvA00

Image of CATH 4ijvB01

4ijvB01

CATH Domain 4ijvB01

Image of CATH 4ijvD01

4ijvD01

CATH Domain 4ijvD01

Image of CATH 4ijvE00

4ijvE00

CATH Domain 4ijvE00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	30 Jun, 2014	Chopped
B	30 Jun, 2014	Chopped
D	30 Jun, 2014	Chopped
E	30 Jun, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4ijvA00	03 Jul, 2014	3.40.50.720	Assigned
4ijvB01	03 Jul, 2014	3.40.50.720	Assigned
4ijvD01	03 Jul, 2014	3.40.50.720	Assigned
4ijvE00	03 Jul, 2014	3.40.50.720	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1