PDB 4igs

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PDB Links
Overview

PDB Information

PDB	4IGS
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design. Cousido-Siah, A., Ruiz, F.X., Mitschler, A., Porte, S., de Lera, A.R., Martin, M.J., Manzanaro, S., de la Fuente, J.A., Terwesten, F., Betz, M., Klebe, G., Farres, J., Pares, X., Podjarny, A. Acta Crystallogr.,Sect.D
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2012-12-18
Resolution	0.850
CATH Insert Date	23 Mar, 2014

PDB Images (3)

Image of CATH 4igs

4igs

PDB 4igs

Image of CATH 4igsA

4igsA

PDB Chain 4igsA

Image of CATH 4igsA00

4igsA00

CATH Domain 4igsA00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	24 Mar, 2014	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4igsA00	17 Apr, 2014	3.20.20.100	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P15121	ALDR_HUMAN	Homo sapiens	Aldo-keto reductase family 1 member B1