PDB 4idv

PDB Information

PDB4IDV
MethodX-RAY DIFFRACTION
Host Organism
Gene SourceHomo sapiens
Primary Citation
Inhibiting NF-KB-inducing kinase (NIK): Discovery, structure-based design, synthesis, structure activity relationship, and co-crystal structures
Li, K., McGee, L.R., Fisher, B., Sudom, A., Liu, J., Rubenstein, S.M., Anwer, M.K., Cushing, T.D., Shin, Y., Ayres, M., Lee, F., Eksterowicz, J., Faulder, P., Waszkowycz, B., Plotnikova, O., Farrelly, E., Xiao, S.H., Chen, G., Wang, Z.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2012-12-13
Resolution2.900
CATH Insert Date07 Jul, 2013

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped
C 08 Jul, 2013 Chopped
D 08 Jul, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4idvA01 27 Aug, 2013 3.30.200.20 Assigned
4idvA02 27 Aug, 2013 1.10.510.10 Assigned
4idvB01 27 Aug, 2013 3.30.200.20 Assigned
4idvB02 27 Aug, 2013 1.10.510.10 Assigned
4idvC01 27 Aug, 2013 3.30.200.20 Assigned
4idvC02 27 Aug, 2013 1.10.510.10 Assigned
4idvD01 27 Aug, 2013 3.30.200.20 Assigned
4idvD02 27 Aug, 2013 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q99558 M3K14_HUMAN Homo sapiens Mitogen-activated protein kinase kinase kinase 14
Q99558 M3K14_HUMAN Homo sapiens Mitogen-activated protein kinase kinase kinase 14
Q99558 M3K14_HUMAN Homo sapiens Mitogen-activated protein kinase kinase kinase 14
Q99558 M3K14_HUMAN Homo sapiens Mitogen-activated protein kinase kinase kinase 14