PDB 4id7

PDB Information

PDB4ID7
MethodX-RAY DIFFRACTION
Host Organism
Gene SourceHomo sapiens
Primary Citation
Discovery of potent, selective and orally bioavailable imidazo[1,5-a]pyrazine derived ACK1 inhibitors.
Jin, M., Wang, J., Kleinberg, A., Kadalbajoo, M., Siu, K.W., Cooke, A., Bittner, M.A., Yao, Y., Thelemann, A., Ji, Q., Bhagwat, S., Mulvihill, K.M., Rechka, J.A., Pachter, J.A., Crew, A.P., Epstein, D., Mulvihill, M.J.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2012-12-11
Resolution3.000
CATH Insert Date03 Feb, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 04 Feb, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4id7A01 14 Aug, 2013 3.30.200.20 Assigned
4id7A02 14 Aug, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q07912 ACK1_HUMAN Homo sapiens Activated CDC42 kinase 1